We present the results of a systematic search for quasars in the Catalina Real-time Transient Survey exhibiting both strong photometric and spectroscopic variability over a decadal baseline. We identify 73 sources with specific patterns of optical and mid-IR photometric behavior and a defined spectroscopic change. These arcsecChanging-State arcsec quasars (CSQs) form a higher luminosity sample to complement existing sets of arcsecChanging-Look arcsec AGN and quasars in the literature. The CSQs (by selection) exhibit larger photometric variability than the CLQs. The spectroscopic variability is marginally stronger in the CSQs than CLQs as defined by the change in H